Comparative Analysis of Nucleotide and Amino Acid Sequences of Human Rhinovirus Genes of Global Strain Project Report

Abstract

This abstract describes a Comparative analysis of nucleotide and amino acid sequence of human rhinovirus gene of global strain to identify phylogenetic analysis and percentage identity matrix any variations in the genetic makeup that may affect the pathogenicity and immunogenicity of the virus. The comparison will be conducted using sequence analysis, based on the nucleotide and the amino acid sequence to identify any differences in the genes and other various factors like evolutionary relationships. Understanding the genetic basis of virulence and immunogenicity is crucial for the development of effective control strategies. Multiple global strains, were analysed using advanced bioinformatics tools. Comparative genomics approaches, phylogenetic analysis, were employed to identify and characterize the virulence and immunogenic genes. This study will provide valuable insights into the genetic diversity of Rhinovirusspecies and its impact on the pathogenicity and immunogenicity of the virus. This study is significant, as it will contribute to the understanding of the molecular epidemiology of human rhinovirus and may aid in the development of effective control strategies for this infectious disease. Additionally, strainspecific variations in virulence genes were observed, highlighting the genetic diversity within the rhinovirus population. This study provides valuable insights into the genetic determinants of virulence and immunogenicity in human rhinovirus. The findings contribute to our understanding of the molecular basis of pathogenesis and host immune response, paving the way for the development of improved diagnostic tools, vaccines, and control strategies.